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NEtFOSAA

N-ethyl perfluorooctanesulfonamidoacetic acid

CAS 2991-50-6C12H8F17NO4S
Long-chain PFAS
EPA federal limit
No federal limit
Detected in
10,294 systems
Regulatory status
Unregulated (UCMR 5)

What is NEtFOSAA?

N-ethyl perfluorooctanesulfonamidoacetic acid, or NEtFOSAA, is a man-made chemical that belongs to the PFAS family, a group of thousands of chemicals often called "forever chemicals" because they break down very slowly in the environment and in the human body. NEtFOSAA is classified as a "precursor" PFAS, meaning it can transform into other harmful PFAS compounds over time. Like all PFAS, it contains very strong chemical bonds that make it extremely resistant to breaking apart.

Where does it come from?

NEtFOSAA has been used in industrial processes and in the making of consumer products designed to resist water, grease, and stains. It is associated with products like stain-resistant carpets and fabrics, food packaging with grease-proof coatings, and certain industrial surface treatments. It can enter the environment through manufacturing waste and the breakdown of older consumer products.

Health concerns

Research on NEtFOSAA specifically is limited compared to more widely studied PFAS compounds like PFOA or PFOS. Because it can break down into those better-studied chemicals, some researchers believe it may carry similar risks, which have been associated in studies with effects on the liver, immune system, and thyroid. However, the direct evidence for NEtFOSAA itself is preliminary and comes mostly from laboratory studies rather than large human studies. If you have specific health concerns, consult a healthcare provider.

EPA standard

The EPA has not established a Maximum Contaminant Level (MCL) — a legal limit for how much of a chemical is allowed in drinking water — for NEtFOSAA. This means public water systems are not currently required to test for or limit this compound. Without a federal standard, there is no guaranteed level of protection for this chemical in tap water.

What you can do

If NEtFOSAA is detected in your water, the EPA and research studies support using a reverse osmosis filter or activated carbon filter, as both have shown effectiveness at reducing PFAS compounds in drinking water. Ion exchange filters are another option shown to reduce PFAS levels. Remember that boiling water does not remove PFAS — it can actually concentrate them.

About this summary: Narrative text on this page was drafted by an AI model (claude-sonnet-4-6) from EPA UCMR 5 data and reviewed before publication. The numeric data above is reported by water utilities directly to the EPA. If you spot an error, email data@checkyourwater.org.

Molecular structure

Molecular structure of N-ethyl perfluorooctanesulfonamidoacetic acid
Source: PubChem

Learn more about NEtFOSAA